Quantum-Chemical Descriptors of Hydroxychloroquine and Remdesivir

bio-process

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged as a global pandemic that is severely affecting our daily life, economy, and putting tremendous pressure on the healthcare infrastructure. Undoubtedly, this is one of the greatest challenges faced by humankind after the World War II. Faced with the unprecedented nature of COVID-19, many vaccines, drug molecules have been fast-tracked in Phase I and Phase II trials.  Unfortunately, there is still no proper treatment available till date1.  However, several existing drug molecules such as ribavirin, interferon, lopinavir-ritonavir, corticosteroids, have been used in patients with SARS or MERS. Although the efficacy of some …

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